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R e g e n s p o r t s o r t h o

Mesenchymal Stem Cell Transplantation

At ReGenSport Ortho Clinic, under the expert care of Dr. Sanjay Kapoor, we specialize in advanced regenerative treatments, including Mesenchymal Stem Cell (MSC) Transplantation for Osteoarthritis (OA) of the Knee & Hip and Avascular Necrosis (AVN) of the Hip. With 24+ years of experience, Dr. Kapoor is at the forefront of orthopedic regenerative medicine, offering patients cutting-edge solutions for joint preservation and pain relief.

Understanding Mesenchymal Stem Cells (MSCs)

Mesenchymal Stem Cells (MSCs) are multipotent cells capable of differentiating into various cell types, including cartilage, bone, and fat cells. These cells play a crucial role in tissue repair and regeneration, making them an effective treatment for degenerative joint conditions like Osteoarthritis (OA) and Avascular Necrosis (AVN).

How MSC Transplantation Works

MSC therapy involves harvesting stem cells from the patient’s own body (typically from bone marrow or adipose tissue), processing them, and injecting them into the affected joint. These stem cells help:

  • Reduce inflammation
  • Stimulate cartilage regeneration
  • Enhance blood supply to damaged tissues
  • Slow down disease progression
  • Provide long-term pain relief

Mesenchymal Stem Cell Transplantation for Osteoarthritis (OA) of the Knee & Hip

What is Osteoarthritis (OA)?

Osteoarthritis (OA) is a chronic degenerative joint disease that leads to cartilage breakdown, resulting in pain, stiffness, and reduced mobility. It is most common in weight-bearing joints like the knee and hip.

How MSC Therapy Helps in OA?

MSC therapy provides an innovative approach to treating OA of the knee and hip by:

  • Promoting cartilage repair: MSCs help rebuild damaged cartilage and restore joint function.
  • Reducing pain and inflammation: The anti-inflammatory properties of MSCs help reduce swelling and discomfort.
  • Delaying or preventing surgery: Many patients experience significant improvement without requiring joint replacement surgery.
  • Enhancing joint lubrication: MSCs improve the production of natural lubricants in the joint, enhancing mobility.

Benefits of MSC Transplantation for OA

  • Minimally invasive procedure
  • No risk of rejection (since the cells come from the patient’s own body)
  • Faster recovery compared to surgical interventions

Long-term pain relief and improved joint function

Mesenchymal Stem Cell Transplantation for Avascular Necrosis (AVN) of the Hip

What is Avascular Necrosis (AVN)?

Avascular Necrosis (AVN) is a condition where the blood supply to the bone is disrupted, leading to the death of bone tissue. The hip joint is the most commonly affected area, causing severe pain, joint collapse, and restricted movement.

How MSC Therapy Helps in AVN?

MSC transplantation offers a non-surgical solution for AVN by:

  • Promoting bone regeneration: MSCs differentiate into bone cells, helping to restore damaged bone tissue.
  • Enhancing blood vessel formation (angiogenesis): MSCs stimulate new blood vessel growth, improving blood supply to the affected area.
  • Reducing pain and delaying joint replacement: MSC therapy provides an effective alternative to total hip replacement in early to mid-stage AVN.

Stages of AVN and MSC Therapy

MSC therapy is most effective in early and mid-stages (Stage I & II) before the bone collapses. However, in later stages, MSCs can still help reduce symptoms and slow disease progression.

Benefits of MSC Transplantation for AVN

  • Prevents further bone damage
  • Improves hip joint function
  • Delays or eliminates the need for surgery
  • Natural healing with minimal side effects

The MSC Transplantation Procedure at ReGenSport Ortho Clinic

Step 1: Consultation & Diagnosis

Dr. Sanjay Kapoor conducts a comprehensive clinical assessment and advanced imaging (MRI/X-rays) to determine eligibility for MSC therapy.

Step 2: Stem Cell Harvesting

  • Bone Marrow-Derived MSCs: Extracted from the patient’s hip bone (iliac crest).
  • Adipose-Derived MSCs: Collected from the patient’s abdominal fat using a minimally invasive liposuction technique.

Step 3: Stem Cell Processing

The collected MSCs are processed and concentrated in a specialized laboratory to enhance their therapeutic potential.

Step 4: Injection into the Affected Joint

The concentrated MSCs are injected directly into the affected joint under ultrasound or fluoroscopic guidance for precision.

Step 5: Post-Treatment Rehabilitation

Patients undergo a tailored rehabilitation program that includes physiotherapy, lifestyle modifications, and dietary advice to optimize recovery and joint health.

Why Choose ReGenSport Ortho Clinic for MSC Therapy?

  • Led by Dr. Sanjay Kapoor, a renowned orthopedic expert with 24+ years of experience in regenerative medicine.
  • State-of-the-art facilities with advanced imaging and stem cell processing labs.
  • Personalized treatment plans tailored to individual patient needs.
  • High success rates in treating OA and AVN with MSC therapy.
  • Minimal downtime and faster recovery compared to traditional surgical options.

Frequently Asked Questions (FAQs)

  1. Who is an ideal candidate for MSC therapy?

Patients with early to moderate OA or AVN who are looking for a non-surgical treatment option are ideal candidates.

  1. How long does the procedure take?

The procedure is typically completed in a few hours, and patients can go home the same day.

  1. When will I see results?

Most patients experience pain relief and improved joint function within 4-6 weeks, with continued improvement over several months.

  1. Are there any side effects?

Since MSC therapy uses the patient’s own cells, the risk of complications is minimal. Some patients may experience mild swelling or discomfort at the injection site.

  1. Will I need multiple treatments?

The need for repeat treatments varies. Some patients experience long-term relief with a single session, while others may benefit from additional sessions.

Book Your Consultation with Dr. Sanjay Kapoor

If you are suffering from Osteoarthritis of the knee or hip or Avascular Necrosis of the hip, Mesenchymal Stem Cell Transplantation at ReGenSport Ortho Clinic can help restore mobility and relieve pain.

Contact us today to schedule your appointment and explore the benefits of regenerative medicine!